Anemic Salmon

	Infectious Salmon Anemia Virus A small project about ISAVirus brought to you by a group of Year 2 MBIO students from Ngee Ann Polytechnic. Click on the pastel orange box on the left for the names of the students involved in this project. Thank you. :) Students MBIO 2F02 Chow Qian Ting Lau Wailing Nur Afiah Bte Shahrudin Nurmahirah Bte Muhd Zaini credits This layout is made and presented to you by ohfudge!, with the colours from Colourlovers. Skin can be found here.
Introduction Thursday, 26 January 2012 @ 12:51 Infectious Salmon Anemia Virus (ISAV) is a piscine orthomyxovirus. This virus causes high mortalities in aqua life worldwide. Its structure is an enveloped virus with a genome consisting of eight negative sense single-stranded RNA segments encoding at least 10 proteins. The ISAV has small projections on its surface that is similar to a mushroom-shape. ISAV contains 4 major polypeptides of putative viral origins: estimated molecular sizes of 71, 53, 43, 24 kDa. The diameter of virion can be in a range of 130nm to 140nm(slightly larger than influenza viruses). ISAV shows higher functional similarity to bovine or porcine torovirus and bovine coronavirus HE proteins and influenza C virus HE fusion protein. ISAV can reach maximum replication at 15˚C(slightly lower than influenza viruses). Trypsin, which are commonly found in cell culture medium enhances viral replication. Viral replication occurs in the nucleus of host cell(salmon). The replication cycle of ISAV is similar to the replication cycle of the Influenza A virus. Structural, morphological, physiochemical properties have determined where it belongs in the viral classification: Orthomyxoviridae.