Infectious Salmon Anemia Virus

A small project about ISAVirus brought to you by a group of Year 2 MBIO students from Ngee Ann Polytechnic.

Click on the pastel orange box on the left for the names of the students involved in this project.

Thank you.

:)

Symptoms
Thursday, 26 January 2012 @ 12:21
Unlike mammals, red blood cells of fish have DNA and causes them to be infected with viruses. ISAV causes severe anemia, resulting pale gills of infected fish. They may swim close to the water surface, gulping for air. Fish may develop a “pop-eye” appearance (exopthalmos). Other symptoms may include lethargy, leukopenia, ascites, darkened skin and increased mortality. Hemorrhages may also be found in the anterior chamber of eye. In Chile, Jaundice on the ventral portion of the body has been reported among Atlantic salmon.

The disease can also develop without the fish showing any external signs of illness. The fish maintain a normal appetite and then they suddenly die. The disease can progress slowly throughout an infected farm and the death rates may approach 100%.

Post-mortem examination of the fish has shown a wide range of causes of death. The gills are pale and the skin can the darkened and Exophthalmia may also be seen. Yellow- or blood-tinged fluid may be found in the peritoneal and pericardial cavities. Petechiae, which may be extensive, can usually be found on various organs and tissues, including the eye, the internal organs, the visceral fat and the skeletal muscles.

The liver and spleen may be swollen, congested, necrosed or partially dead. In some cases, the spleen may turned dark brown or even black in colour, and it may be covered with a layer of fibrin. The kidney may also be swollen and dark, blood and liquid may exuded from the cut surface. The gastrointestinal tract may also be congested, but blood is not usually found in the intestinal lumen if the carcass is fresh.

The circulatory system may stop working, and the blood may be contaminated with lots of dead blood cells. Red blood cells which are still present in the circulatory system often burst easily and the numbers of immature and damaged blood cells increased.